BIOPEP-UWM: Report

ID 9173
Name ACE inhibitor
sequence
RG

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 231.2516 Monoisotopic mass 231.1328
IC50 :
1200.00 µM



Bibliographic data:
Authors
Cheung H. S., Wang F. L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence. Journal of Biological Chemistry, 255, 401-407, 1980
Year Source
1980 Journal



Additional information:

BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCCNC(N)=N)C(=O)NCC(O)=O

InChI=1S/C8H17N5O3/c9-5(2-1-3-12-8(10)11)7(16)13-4-6(14)15/h5H,1-4,9H2,(H,13,16)(H,14,15)(H4,10,11,12)/t5-/m0/s1

InChIKey=XUUXCWCKKCZEAW-YFKPBYRVSA-N

Inhibitor of the Leucyltransferase (EC 2.3.2.6) according to the BRENDA database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8882)
Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 8)
Salty taste enhancing peptide according to the BIOPEP database of sensory peptides and amino acids (ID 422)



Database reference:
ACToR: ID 2418-67-9

AHTPDB: ID 1479; 5433; 5448

BindingDB: ID 50188522

BioPepDB: ID biopep01186

BIOPEP-UWM database of bioactive peptides: ID 8882

BIOPEP-UWM database of sensory peptides and amino acids: ID 8; 422

BRENDA: Ligand Arg-Gly

ChEMBL: ID CHEMBL382777

ChemIDplus: ID 002418679

ChemSpider: ID 4251526

EPA DSSTox: ID DTXCID70101376

EROP-Moscow: ID E10392

J-GLOBAL ID: 200907074614271802

Nikkaji: ID J80.480K

PubChem: CID 5074903

SATPdb: ID satpdb12415

SureChEMBL: ID SCHEMBL2117673

ZINC: ID ZINC02545093