BIOPEP-UWM: Report

ID 9187
Name ACE inhibitor
sequence
MEGAQEAQGD
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
10
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1035.0422 Monoisotopic mass 1034.3960
IC50 :
15.90 µM


Bibliographic data:
Authors
Zhao Y. H., Li B. F., Dong S. Y., Zhao X., Wang J. F., Zeng M. Y.
Title
A novel ACE inhibitory peptide isolated from Acaudina molpadioidea hydrolysate. Peptides, 30, 1028-1033, 2009
Year Source
2009 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)O

InChI=1S/C39H62N12O19S/c1-17(45-27(54)15-43-36(66)21(6-10-29(56)57)50-34(64)19(40)12-13-71-3)32(62)49-22(5-9-26(42)53)38(68)51-23(7-11-30(58)59)37(67)46-18(2)33(63)48-20(4-8-25(41)52)35(65)44-16-28(55)47-24(39(69)70)14-31(60)61/h17-24H,4-16,40H2,1-3H3,(H2,41,52)(H2,42,53)(H,43,66)(H,44,65)(H,45,54)(H,46,67)(H,47,55)(H,48,63)(H,49,62)(H,50,64)(H,51,68)(H,56,57)(H,58,59)(H,60,61)(H,69,70)/t17-,18-,19-,20-,21-,22-,23-,24-/m0/s1

InChIKey: MPBVRULPSLWUEZ-OPKHLUCYSA-N

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 1048, 2706, 2831, 2924, 3687, 4217, 5048, 6184

EROP-Moscow: ID E09400

PepBank: Peptide MEGAQEAQGD

SATPdb: ID satpdb11868