BIOPEP-UWM: Report

ID 9198
Name Alpha-amylase inhibitor
sequence
FFRSKLLSDGAAAAKGALLPQYW
Function:
Inhibitor of alpha-amylase (EC 3.2.1.1)
 
Number of residues
23
Activity code
aami
Activity :
alpha-amylase inhibitor
Chemical mass 2510.8783 Monoisotopic mass 2509.3440
IC50 :
0.02 µM


Bibliographic data:
Authors
Siow H.-L., Gan C.-Y.
Title
Extraction, identification, and structure–activity relationship of antioxidative and alpha-amylase inhibitory peptides from cumin seeds (Cuminum cyminum). J. Funct. Foods, 22, 1-12, 2016
Year Source
2016 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI=1S/C119H180N30O30/c1-62(2)48-83(110(170)145-89(51-65(7)8)117(177)149-47-27-37-93(149)116(176)138-82(42-43-94(123)153)108(168)143-87(54-73-38-40-75(152)41-39-73)113(173)146-90(118(178)179)55-74-57-127-78-33-21-20-32-76(74)78)139-101(161)67(10)131-95(154)58-128-104(164)79(34-22-24-44-120)135-102(162)70(13)134-100(160)69(12)133-99(159)68(11)132-98(158)66(9)130-96(155)59-129-105(165)88(56-97(156)157)144-115(175)92(61-151)148-111(171)85(50-64(5)6)142-109(169)84(49-63(3)4)141-106(166)80(35-23-25-45-121)137-114(174)91(60-150)147-107(167)81(36-26-46-126-119(124)125)136-112(172)86(53-72-30-18-15-19-31-72)140-103(163)77(122)52-71-28-16-14-17-29-71/h14-21,28-33,38-41,57,62-70,77,79-93,127,150-152H,22-27,34-37,42-56,58-61,120-122H2,1-13H3,(H2,123,153)(H,128,164)(H,129,165)(H,130,155)(H,131,154)(H,132,158)(H,133,159)(H,134,160)(H,135,162)(H,136,172)(H,137,174)(H,138,176)(H,139,161)(H,140,163)(H,141,166)(H,142,169)(H,143,168)(H,144,175)(H,145,170)(H,146,173)(H,147,167)(H,148,171)(H,156,157)(H,178,179)(H4,124,125,126)/t66-,67-,68-,69-,70-,77-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-/m0/s1

InChIKey: KPVDLTOYELAYFZ-FYWVDWBNSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9197)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9197