BIOPEP-UWM: Report

ID 9200
Name Alpha-amylase inhibitor
sequence
RCMAFLLSDGAAAAQQLLPQYW
Function:
Inhibitor of alpha-amylase (EC 3.2.1.1)
 
Number of residues
22
Activity code
aami
Activity :
alpha-amylase inhibitor
Chemical mass 2453.8313 Monoisotopic mass 2452.1993
IC50 :
0.04 µM


Bibliographic data:
Authors
Siow H.-L., Gan C.-Y.
Title
Extraction, identification, and structure–activity relationship of antioxidative and alpha-amylase inhibitory peptides from cumin seeds (Cuminum cyminum). J. Funct. Foods, 22, 1-12, 2016
Year Source
2016 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)O

InChI=1S/C111H169N29O30S2/c1-54(2)42-74(133-104(163)77(46-63-22-16-15-17-23-63)130-94(153)62(13)125-97(156)73(38-41-172-14)128-107(166)83(53-171)139-95(154)68(112)25-20-39-118-111(116)117)101(160)132-76(44-56(5)6)103(162)138-82(52-141)106(165)135-79(49-89(147)148)96(155)120-51-88(146)121-58(9)90(149)122-59(10)91(150)123-60(11)92(151)124-61(12)93(152)126-70(32-35-85(113)143)98(157)127-71(33-36-86(114)144)99(158)131-75(43-55(3)4)102(161)136-80(45-57(7)8)109(168)140-40-21-27-84(140)108(167)129-72(34-37-87(115)145)100(159)134-78(47-64-28-30-66(142)31-29-64)105(164)137-81(110(169)170)48-65-50-119-69-26-19-18-24-67(65)69/h15-19,22-24,26,28-31,50,54-62,68,70-84,119,141-142,171H,20-21,25,27,32-49,51-53,112H2,1-14H3,(H2,113,143)(H2,114,144)(H2,115,145)(H,120,155)(H,121,146)(H,122,149)(H,123,150)(H,124,151)(H,125,156)(H,126,152)(H,127,157)(H,128,166)(H,129,167)(H,130,153)(H,131,158)(H,132,160)(H,133,163)(H,134,159)(H,135,165)(H,136,161)(H,137,164)(H,138,162)(H,139,154)(H,147,148)(H,169,170)(H4,116,117,118)/t58-,59-,60-,61-,62-,68-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-/m0/s1

InChIKey: WTCZJKPIVNVDQJ-AROXQYLNSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9199)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9199