BIOPEP-UWM: Report

ID 9203
Name ACE inhibitor
sequence
VVCVPW

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 701.8755 Monoisotopic mass 701.3559
IC50 :
4.07 µM



Bibliographic data:
Authors
Liu R., Zhu Y., Chen J., Wu H., Shi L., Wang X., Wang L.
Title
Characterization of ACE inhibitory peptides from Mactra veneriformis hydrolysate by nano-liquid chromatography electrospray ionization mass spectrometry (Nano-LC-ESI-MS) and molecular docking. Mar. Drugs, 12, 3917-3928, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)O

InChI=1S/C34H51N7O7S/c1-17(2)26(35)31(44)39-27(18(3)4)32(45)38-24(16-49)29(42)40-28(19(5)6)33(46)41-13-9-12-25(41)30(43)37-23(34(47)48)14-20-15-36-22-11-8-7-10-21(20)22/h7-8,10-11,15,17-19,23-28,36,49H,9,12-14,16,35H2,1-6H3,(H,37,43)(H,38,45)(H,39,44)(H,40,42)(H,47,48)/t23-,24-,25-,26-,27-,28-/m0/s1

InChIKey: GLGGIHGQCQPJRL-QUQVWLGBSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference: