BIOPEP-UWM: Report

ID 9204
Name ACE inhibitor
sequence
LYHVL

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 643.7722 Monoisotopic mass 643.3682
IC50 :
17.50 µM



Bibliographic data:
Authors
Liu R., Zhu Y., Chen J., Wu H., Shi L., Wang X., Wang L.
Title
Characterization of ACE inhibitory peptides from Mactra veneriformis hydrolysate by nano-liquid chromatography electrospray ionization mass spectrometry (Nano-LC-ESI-MS) and molecular docking. Mar. Drugs, 12, 3917-3928, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C32H49N7O7/c1-17(2)11-23(33)28(41)36-24(13-20-7-9-22(40)10-8-20)29(42)37-25(14-21-15-34-16-35-21)30(43)39-27(19(5)6)31(44)38-26(32(45)46)12-18(3)4/h7-10,15-19,23-27,40H,11-14,33H2,1-6H3,(H,34,35)(H,36,41)(H,37,42)(H,38,44)(H,39,43)(H,45,46)/t23-,24-,25-,26-,27-/m0/s1

InChIKey: YKHBNANBWRTPRJ-IRGGMKSGSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference: