BIOPEP-UWM: Report

ID 9207
Name ACE inhibitor
sequence
PLFPK

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 600.7475 Monoisotopic mass 600.3624
IC50 :
41.30 µM



Bibliographic data:
Authors
Liu R., Zhu Y., Chen J., Wu H., Shi L., Wang X., Wang L.
Title
Characterization of ACE inhibitory peptides from Mactra veneriformis hydrolysate by nano-liquid chromatography electrospray ionization mass spectrometry (Nano-LC-ESI-MS) and molecular docking. Mar. Drugs, 12, 3917-3928, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C31H48N6O6/c1-20(2)18-24(35-27(38)22-13-8-16-33-22)28(39)36-25(19-21-10-4-3-5-11-21)30(41)37-17-9-14-26(37)29(40)34-23(31(42)43)12-6-7-15-32/h3-5,10-11,20,22-26,33H,6-9,12-19,32H2,1-2H3,(H,34,40)(H,35,38)(H,36,39)(H,42,43)/t22-,23-,24-,25-,26-/m0/s1

InChIKey: FLEVYBGXEDCYAR-LROMGURASA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001





Database reference: