BIOPEP-UWM: Report

ID 9210
Name ACE inhibitor
sequence
LFVAAP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 616.7469 Monoisotopic mass 616.3573
IC50 :
70.20 µM



Bibliographic data:
Authors
Liu R., Zhu Y., Chen J., Wu H., Shi L., Wang X., Wang L.
Title
Characterization of ACE inhibitory peptides from Mactra veneriformis hydrolysate by nano-liquid chromatography electrospray ionization mass spectrometry (Nano-LC-ESI-MS) and molecular docking. Mar. Drugs, 12, 3917-3928, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C31H48N6O7/c1-17(2)15-22(32)27(39)35-23(16-21-11-8-7-9-12-21)28(40)36-25(18(3)4)29(41)33-19(5)26(38)34-20(6)30(42)37-14-10-13-24(37)31(43)44/h7-9,11-12,17-20,22-25H,10,13-16,32H2,1-6H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)(H,43,44)/t19-,20-,22-,23-,24-,25-/m0/s1

InChIKey: KGYGETLKDSADNZ-OKJKELKDSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference: