BIOPEP-UWM: Report

ID 9211
Name ACE inhibitor
sequence
FKR

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 449.5457 Monoisotopic mass 449.2743
IC50 :
77.90 µM



Bibliographic data:
Authors
Liu R., Zhu Y., Chen J., Wu H., Shi L., Wang X., Wang L.
Title
Characterization of ACE inhibitory peptides from Mactra veneriformis hydrolysate by nano-liquid chromatography electrospray ionization mass spectrometry (Nano-LC-ESI-MS) and molecular docking. Mar. Drugs, 12, 3917-3928, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C21H35N7O4/c22-11-5-4-9-16(27-18(29)15(23)13-14-7-2-1-3-8-14)19(30)28-17(20(31)32)10-6-12-26-21(24)25/h1-3,7-8,15-17H,4-6,9-13,22-23H2,(H,27,29)(H,28,30)(H,31,32)(H4,24,25,26)/t15-,16-,17-/m0/s1

InChIKey=DMEYUTSDVRCWRS-ULQDDVLXSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Antiviral peptide according to the BIOPEP-UWM database of bioactive peptides, the ChEMBL database, the PubChem database




Database reference:
ChEBI: ID 161674

ChEMBL: ID CHEMBL1271468

ChemSpider: ID 26363276

DFBP: ID DFBPACEI1087

EROP-Moscow: ID E24933

Metabolomics Workbench: ID 84477

PubChem: CID 52943303

UniChem: ID 959675

Wikidata: ID Q106027804

ZINC: ID ZINC000039809575