BIOPEP-UWM: Report

ID 9248
Name ACE inhibitor
sequence
VLSRYP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 733.8532 Monoisotopic mass 733.4110
IC50 :
36.70 µM



Bibliographic data:
Authors
Li Y., Sadiq F. A., Liu T. J., Chen J. C., He G. Q.
Title
Purification and identification of novel peptides with inhibitory effect against angiotensin I-converting enzyme and optimization of process conditions in milk fermented with the yeast Kluyveromyces marxianus. J. Funct. Foods., 2015, 16:278-288.
Year Source
2015 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C34H55N9O9/c1-18(2)15-23(40-31(49)27(35)19(3)4)29(47)42-25(17-44)30(48)39-22(7-5-13-38-34(36)37)28(46)41-24(16-20-9-11-21(45)12-10-20)32(50)43-14-6-8-26(43)33(51)52/h9-12,18-19,22-27,44-45H,5-8,13-17,35H2,1-4H3,(H,39,48)(H,40,49)(H,41,46)(H,42,47)(H,51,52)(H4,36,37,38)/t22-,23-,24-,25-,26-,27-/m0/s1

InChIKey: GWMMOCNECGMPES-QCOJBMJGSA-N



Database reference:
MBPDB: Peptide VLSRYP