BIOPEP-UWM: Report

ID 9250
Name ACE inhibitor
sequence
VPSERYL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 862.9669 Monoisotopic mass 862.4534
IC50 :
232.80 µM


Bibliographic data:
Authors
Sieber R., Bütikofer U., Egger C., Portmann R., Walther B., Weschsler D.
Title
ACE-inhibitory activity and ACE-inhibiting peptides in different cheese varieties. Dairy Sci. Technol., 2010, 90:47-73.
Year Source
2010 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C39H62N10O12/c1-20(2)17-27(38(60)61)47-34(56)26(18-22-9-11-23(51)12-10-22)46-32(54)24(7-5-15-43-39(41)42)44-33(55)25(13-14-30(52)53)45-35(57)28(19-50)48-36(58)29-8-6-16-49(29)37(59)31(40)21(3)4/h9-12,20-21,24-29,31,50-51H,5-8,13-19,40H2,1-4H3,(H,44,55)(H,45,57)(H,46,54)(H,47,56)(H,48,58)(H,52,53)(H,60,61)(H4,41,42,43)/t24-,25-,26-,27-,28-,29-,31-/m0/s1

InChIKey: VTSANRNVZZOBGM-IRQHXVELSA-N


Database reference:
AHTPDB: ID 1339, 5705

EROP-Moscow: ID E10836

MBPDB: Peptide VPSERYL

SATPdb: ID satpdb28877