BIOPEP-UWM: Report

ID 9251
Name ACE inhibitor
sequence
VVVPPF

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 656.8106 Monoisotopic mass 656.3885
EC50 :
1.18 µM



Bibliographic data:
Authors
QuirĂ³s A., Contreras M. M., Ramos M., Amigo L., Recio I.
Title
Stability to gastrointestinal enzymes and structure-activity relationship of β-casein-peptides with antihypertensive properties. Peptides. 2009, 30:1848-1853.
Year Source
2009 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccccc1)C(O)=O

InChI=1S/C34H52N6O7/c1-19(2)26(35)30(42)37-27(20(3)4)31(43)38-28(21(5)6)33(45)40-17-11-15-25(40)32(44)39-16-10-14-24(39)29(41)36-23(34(46)47)18-22-12-8-7-9-13-22/h7-9,12-13,19-21,23-28H,10-11,14-18,35H2,1-6H3,(H,36,41)(H,37,42)(H,38,43)(H,46,47)/t23-,24-,25-,26-,27-,28-/m0/s1

InChIKey: JSZQEWKLZMKMKS-QUQVWLGBSA-N



Database reference:
AHTPDB: ID 2534, 4335, 5817

SATPdb: ID satpdb16462