BIOPEP-UWM: Report

ID 9254
Name ACE inhibitor
sequence
YQKFPQY
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 973.0790 Monoisotopic mass 972.4690
IC50 :
20.08 µM


Bibliographic data:
Authors
Contreras M. M., Carrón R., Montero M. J., Ramos M., Recio I.
Title
Novel casein-derived peptides with antihypertensive activity. Int. Dairy J. 2009; 19: 566-573.
Year Source
2009 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(O)=O

InChI=1S/C48H64N10O12/c49-23-5-4-9-34(54-44(65)35(19-21-40(51)61)53-42(63)33(50)25-29-11-15-31(59)16-12-29)43(64)56-37(26-28-7-2-1-3-8-28)47(68)58-24-6-10-39(58)46(67)55-36(20-22-41(52)62)45(66)57-38(48(69)70)27-30-13-17-32(60)18-14-30/h1-3,7-8,11-18,33-39,59-60H,4-6,9-10,19-27,49-50H2,(H2,51,61)(H2,52,62)(H,53,63)(H,54,65)(H,55,67)(H,56,64)(H,57,66)(H,69,70)/t33-,34-,35-,36-,37-,38-,39-/m0/s1

InChIKey: TZXMOJGCTZFVLR-ZTYVOHGWSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9261); the MBPDB database


Database reference:
AHTPDB: ID 1720, 1759, 2380, 2613, 2620, 4148, 4280, 5034

BioPepDB: ID biopep01624

BIOPEP-UWM database of bioactive peptides: ID 9261

EROP-Moscow: ID E14712

MBPDB: Peptide YQKFPQY

SATPdb: ID satpdb26998