BIOPEP-UWM: Report
| ID | 9255 |
| Name | Neuropeptide Spinorphin |
| sequence |
| Function: | |||
| Human P2X3 receptor antagonist | |||
| Number of residues | 7 |
Activity code | ne |
| Activity : | neuropeptide |
|||
| Chemical mass | 877.0347 | Monoisotopic mass | 876.4730 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Jung K. Y., Moon H. D., Lee G. E., Lim H. H., Park C. S., Kim Y. C. | |
| Title | |
| Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. J. Med. Chem., 50, 4543-4547, 2007 | |
| Year | Source |
| 2007 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC3=C[N]([H])C4=CC=CC=C34)C(=O)N[C@@H]([C@H](O)C)C(=O)O InChI=1S/C45H64N8O10/c1-23(2)19-31(46)39(56)50-37(25(5)6)43(60)51-36(24(3)4)42(59)49-34(20-27-14-16-29(55)17-15-27)44(61)53-18-10-13-35(53)41(58)48-33(40(57)52-38(26(7)54)45(62)63)21-28-22-47-32-12-9-8-11-30(28)32/h8-9,11-12,14-17,22-26,31,33-38,47,54-55H,10,13,18-21,46H2,1-7H3,(H,48,58)(H,49,59)(H,50,56)(H,51,60)(H,52,57)(H,62,63)/t26-,31+,33+,34+,35+,36+,37+,38+/m1/s1 InChIKey: BXIFNVGZIMFBQB-DYDSHOKNSA-N Cytotoxic peptide according to the EROP-Moscow database Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database (ID 9632) |
| Database reference: |
| ACToR: ID 137201-62-8 BindingDB: ID 50219120 BIOPEP-UWM database of bioactive peptides: ID 9632 ChEMBL: ID CHEMBL395493 ChemIDplus: ID 137201628 ChemSpider: ID 2339355 DSigDB: ID d4ttd_11043, d4ctd_2995 EPA CompTox Dashboard: ID DTXSID70160105 EPA DSSTox: ID DTXCID3082596 EROP-Moscow: ID E01885 Human Metabolome Database: ID HMDB59790 J-GLOBAL: ID 200907027456681757 Nikkaji: ID J555.836K PepBank: Peptide LVVYPWT PubChem: CID 3081832 ZINC: ID ZINC000150339235 |