BIOPEP-UWM: Report

ID 9265
Name ACE inhibitor
sequence
RYDF

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 599.6340 Monoisotopic mass 599.2695
IC50 :
235.00 µM



Bibliographic data:
Authors
Guo M., Chen X., Wu Y., Zhang L., Huang W., Yuan Y., Fang M., Xie J., Wei D.
Title
Angiotensin I-converting enzyme inhibitory peptides from Sipuncula (Phascolosoma esculenta): Purification, identification, molecular docking and antihypertensive effects on spontaneously hypertensive rats. Process Biochem., 63, 84-95, 2017
Year Source
2017 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O

InChI=1S/C28H37N7O8/c29-19(7-4-12-32-28(30)31)24(39)33-20(13-17-8-10-18(36)11-9-17)25(40)34-21(15-23(37)38)26(41)35-22(27(42)43)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-22,36H,4,7,12-15,29H2,(H,33,39)(H,34,40)(H,35,41)(H,37,38)(H,42,43)(H4,30,31,32)/t19-,20-,21-,22-/m0/s1

InChIKey=KOEMLYHDPLGFPD-CMOCDZPBSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference:
EROP-Moscow: ID E24673