BIOPEP-UWM: Report

ID 9343
Name ACE inhibitor
sequence
IQW
Function:
Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 445.5108 Monoisotopic mass 445.2318
IC50 :
0.00 µM


Bibliographic data:
Authors
Majumder K., Chakrabarti S., Morton J.S., Panahi S., Kaufman S., Davidge S.T., Wu J.
Title
Egg-derived ACE-inhibitory peptides IQW and LKP reduce blood pressure in spontaneously hypertensive rats. Food Chem.,13, 50-60, 2015
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@](C(N[C@](C(N[C@](C(O)=O)(Cc1c2ccccc2[nH]c1)[H])=O)(CCC(N)=O)[H])=O)([C@@H](C)CC)[H]

InChI=1S/C22H31N5O5/c1-3-12(2)19(24)21(30)26-16(8-9-18(23)28)20(29)27-17(22(31)32)10-13-11-25-15-7-5-4-6-14(13)15/h4-7,11-12,16-17,19,25H,3,8-10,24H2,1-2H3,(H2,23,28)(H,26,30)(H,27,29)(H,31,32)/t12-,16-,17-,19-/m0/s1

InChIKey: MVLDERGQICFFLL-ZQINRCPSSA-N


Peptide reveals blond pressure lowering activity in vivo.
Majumder K., Chakrabarti S., Morton J.S., Panahi S., Kaufman S., Davidge S.T., Wu J., 2015, Egg-derived ACE-inhibitory peptides IQW and LKP reduce blood pressure in spontaneously hypertensive rats. Food Chem., 13, 50-60

Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9161)


Database reference:
AHTPDB: ID 2042, 2206

BIOPEP-UWM database of bioactive peptides: ID 9161

PubChem: CID 46913346

SATPdb: ID satpdb23379