BIOPEP-UWM: Report

ID 9383
Name HMG-CoA reductase inhibitor
sequence
GGV
Function:
Inhibitor of HMG-CoA reductase (EC 1.1.1.34)
 
Number of residues
3
Activity code
HMGi
Activity :
HMG-CoA reductase inhibitor
Chemical mass 231.2483 Monoisotopic mass 231.1215
EC50 :
0.00 µM


Bibliographic data:
Authors
Soares R. A. M., Mendonca S. S., Castro L. I. A., Menezes A. C. C. C. C., Areas J. A.
Title
Major Peptides from Amaranth (Amaranthus cruentus) Protein Inhibit HMG-CoA Reductase Activity. Int. J. Mol. Sci., 16, 4150-4160, 2015
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](NC(=O)CNC(=O)CN)(C(C)C)C(O)=O

InChI=1S/C9H17N3O4/c1-5(2)8(9(15)16)12-7(14)4-11-6(13)3-10/h5,8H,3-4,10H2,1-2H3,(H,11,13)(H,12,14)(H,15,16)/t8-/m0/s1

InChIKey: OLPPXYMMIARYAL-QMMMGPOBSA-N


HMG-CoA reductase (EC 1.1.1.34) is involved in cholesterol biosynthesis.


Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 107)


Database reference:
ACToR: ID 20274-89-9

AHTPDB: ID 4576; 4860; 5490

BioPepDB: ID biopep00346

BIOPEP-UWM database of sensory peptides and amino acids: ID 107

ChEMBL: ID CHEMBL1221710

ChemIDplus: ID 020274899

ChemSpider: ID 167967

EPA DSSTox: ID DTXCID8096611

J-GLOBAL: ID 200907069869699373

Nikkaji: ID J149.644A

PubChem: ID 193555

SATPdb: ID satpdb17293

SureChEMBL: ID SCHEMBL15756824

ZINC: ID ZINC02165165