BIOPEP-UWM: Report

ID 9385
Name HMG-CoA reductase inhibitor
sequence
VGVL
Function:
Inhibitor of HMG-CoA reductase (EC 1.1.1.34)
 
Number of residues
4
Activity code
HMGi
Activity :
HMG-CoA reductase inhibitor
Chemical mass 386.4850 Monoisotopic mass 386.2521
EC50 :
0.00 µM


Bibliographic data:
Authors
Soares R. A. M., Mendonca S. S, Castro L. I. A., Menezes A. C. C. C. C., Areas J. A.
Title
Major Peptides from Amaranth (Amaranthus cruentus) Protein Inhibit HMG-CoA Reductase Activity. Int. J. Mol. Sci., 16, 4150-4160, 2015
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(C(C)C)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C18H34N4O5/c1-9(2)7-12(18(26)27)21-17(25)15(11(5)6)22-13(23)8-20-16(24)14(19)10(3)4/h9-12,14-15H,7-8,19H2,1-6H3,(H,20,24)(H,21,25)(H,22,23)(H,26,27)/t12-,14-,15-/m0/s1

InChIKey: PNYQKCDETCQZFS-QEJZJMRPSA-N


HMG-CoA reductase (EC 1.1.1.34) is involved in cholesterol biosynthesis.


Database reference: