BIOPEP-UWM: Report

ID 9392
Name Alpha-glucosidase inhibitor
sequence
AGLAPY

Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
6
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 590.6668 Monoisotopic mass 590.3054
EC50 :
0.00 µM



Bibliographic data:
Authors
Yu Z, Yin Y, Zhao W, Yu Y, Liu B, Liu J, Chen F
Title
Novel peptides derived from egg white protein inhibiting alpha-glucosidase. Food Chem 129:1376–1382 (2011)
Year Source
2011 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(N)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(O)=O

InChI=1S/C28H42N6O8/c1-15(2)12-20(32-23(36)14-30-24(37)16(3)29)25(38)31-17(4)27(40)34-11-5-6-22(34)26(39)33-21(28(41)42)13-18-7-9-19(35)10-8-18/h7-10,15-17,20-22,35H,5-6,11-14,29H2,1-4H3,(H,30,37)(H,31,38)(H,32,36)(H,33,39)(H,41,42)/t16-,17-,20-,21-,22-/m0/s1

InChIKey=SSOPPTVGJNTZIJ-NXQKYAITSA-N

Originally, IC50 (µM) of peptide was >150 (see cited paper).

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database



Database reference:
AHTPDB: ID 4481

BioPepDB: ID biopep00017

SATPdb: ID satpdb24428