BIOPEP-UWM: Report

ID 9393
Name Alpha-glucosidase inhibitor
sequence
RVPSL
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
5
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 570.6803 Monoisotopic mass 570.3479
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z, Yin Y, Zhao W, Yu Y, Liu B, Liu J, Chen F
Title
Novel peptides derived from egg white protein inhibiting alpha-glucosidase. Food Chem 129:1376–1382 (2011)
Year Source
2011 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:[H][C@](N)(CCCNC(N)=N)C(=O)N[C@@]([H])(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C25H46N8O7/c1-13(2)11-16(24(39)40)30-21(36)17(12-34)31-22(37)18-8-6-10-33(18)23(38)19(14(3)4)32-20(35)15(26)7-5-9-29-25(27)28/h13-19,34H,5-12,26H2,1-4H3,(H,30,36)(H,31,37)(H,32,35)(H,39,40)(H4,27,28,29)/t15-,16-,17-,18-,19-/m0/s1

InChIKey=IARUETPWBSYXJQ-VMXHOPILSA-N

Originally, IC50 (µM) of peptide was >150 (see cited paper).

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database


Database reference:
AHTPDB: ID 1943, 4471

BioPepDB: ID biopep01227

SATPdb: ID satpdb12091