BIOPEP-UWM: Report

ID 9394
Name Alpha-glucosidase inhibitor
sequence
DHPFLF
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
6
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 774.8605 Monoisotopic mass 774.3689
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z, Yin Y, Zhao W, Yu Y, Liu B, Liu J, Chen F
Title
Novel peptides derived from egg white protein inhibiting alpha-glucosidase. Food Chem 129:1376–1382 (2011)
Year Source
2011 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(O)=O)C(=O)N[C@@]([H])(Cc1cnc[nH]1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(O)=O

InChI=1S/C39H50N8O9/c1-23(2)16-28(35(51)46-31(39(55)56)18-25-12-7-4-8-13-25)43-36(52)29(17-24-10-5-3-6-11-24)44-37(53)32-14-9-15-47(32)38(54)30(19-26-21-41-22-42-26)45-34(50)27(40)20-33(48)49/h3-8,10-13,21-23,27-32H,9,14-20,40H2,1-2H3,(H,41,42)(H,43,52)(H,44,53)(H,45,50)(H,46,51)(H,48,49)(H,55,56)/t27-,28-,29-,30-,31-,32-/m0/s1

InChIKey=UWKOEAGHNGHFBX-JNRWAQIZSA-N

Originally, IC50 (µM) of peptide was >150 (see cited paper).

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database


Database reference:
AHTPDB: ID 4482

BioPepDB: ID biopep00131

SATPdb: ID satpdb17337