BIOPEP-UWM: Report

ID 9395
Name Alpha-glucosidase inhibitor
sequence
HAEIN
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
5
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 582.6052 Monoisotopic mass 582.2753
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z, Yin Y, Zhao W, Yu Y, Liu B, Liu J, Chen F
Title
Novel peptides derived from egg white protein inhibiting alpha-glucosidase. Food Chem 129:1376–1382 (2011)
Year Source
2011 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1cnc[nH]1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C24H38N8O9/c1-4-11(2)19(23(39)31-16(24(40)41)8-17(26)33)32-22(38)15(5-6-18(34)35)30-20(36)12(3)29-21(37)14(25)7-13-9-27-10-28-13/h9-12,14-16,19H,4-8,25H2,1-3H3,(H2,26,33)(H,27,28)(H,29,37)(H,30,36)(H,31,39)(H,32,38)(H,34,35)(H,40,41)/t11-,12-,14-,15-,16-,19-/m0/s1

InChIKey=WRHNPYUHAVYASD-XTPDHVNNSA-N

Originally, IC50 (µM) of peptide was >150 (see cited paper).

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database


Database reference:
AHTPDB: ID 4483

BioPepDB: ID biopep00443

SATPdb: ID satpdb10255