BIOPEP-UWM: Report

ID 9402
Name Alpha-glucosidase inhibitor
sequence
QITKPN
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
6
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 699.7940 Monoisotopic mass 699.3903
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z, Yin Y, Zhao W, Yu Y, Liu B, Liu J, Chen F
Title
Novel peptides derived from egg white protein inhibiting alpha-glucosidase. Food Chem 129:1376–1382 (2011)
Year Source
2011 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCC(N)=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C30H53N9O10/c1-4-15(2)23(37-25(43)17(32)10-11-21(33)41)27(45)38-24(16(3)40)28(46)35-18(8-5-6-12-31)29(47)39-13-7-9-20(39)26(44)36-19(30(48)49)14-22(34)42/h15-20,23-24,40H,4-14,31-32H2,1-3H3,(H2,33,41)(H2,34,42)(H,35,46)(H,36,44)(H,37,43)(H,38,45)(H,48,49)/t15-,16+,17-,18-,19-,20-,23-,24-/m0/s1

InChIKey: LCHADKBJSSGWMP-UCXHCKEJSA-N

Originally, IC50 (µM) of peptide was >150 (see cited paper).



Inhibitor of alpha-amylase (EC 3.2.1.1) according to the BIOPEP-UWM database of bioactive peptides (ID 9414)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9414