BIOPEP-UWM: Report

ID 9406
Name Alpha-glucosidase inhibitor
sequence
LEPINF
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
6
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 731.8341 Monoisotopic mass 731.3841
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z, Yin Y, Zhao W, Yu Y, Liu B, Liu J, Chen F
Title
Novel peptides derived from egg white protein inhibiting alpha-glucosidase. Food Chem 129:1376–1382 (2011)
Year Source
2011 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@](N)(CC(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(Cc1ccccc1)C(O)=O

InChI=1S/C35H53N7O10/c1-5-20(4)29(33(49)39-24(18-27(37)43)31(47)40-25(35(51)52)17-21-10-7-6-8-11-21)41-32(48)26-12-9-15-42(26)34(50)23(13-14-28(44)45)38-30(46)22(36)16-19(2)3/h6-8,10-11,19-20,22-26,29H,5,9,12-18,36H2,1-4H3,(H2,37,43)(H,38,46)(H,39,49)(H,40,47)(H,41,48)(H,44,45)(H,51,52)/t20-,22-,23-,24-,25-,26-,29-/m0/s1

InChIKey=FMWASPQBXFXMLS-YGDYRFLNSA-N

Originally, IC50 (µM) of peptide was >150 (see cited paper).


Inhibitor of alpha-amylase (EC 3.2.1.1) according to the BIOPEP-UWM database of bioactive peptides (ID 9418)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9418