BIOPEP-UWM: Report

ID 9428
Name orphanin FQ/nociceptin
sequence
FGGFTGARKSARKLANQ
Function:
Opioid
 
Number of residues
17
Activity code
op
Activity :
opioid
Chemical mass 1809.0321 Monoisotopic mass 1807.9777
IC50 :
0.00 µM


Bibliographic data:
Authors
Reinscheid R. K., Nothacker H.-P., Bourson A., Ardati A., Henningsen R. A., Bunzow J. R., Grandy D. K., Langen H., Monsma F. J., Civelli O.
Title
Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor. Science, 270 (5237), 792-794, 1995
Year Source
1995 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES:
N[C@@]([H])(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C79H129N27O22/c1-41(2)33-54(72(122)95-44(5)66(116)103-56(36-59(84)110)73(123)102-53(77(127)128)27-28-58(83)109)104-70(120)49(23-13-15-29-80)100-69(119)52(26-18-32-90-79(87)88)99-65(115)43(4)96-75(125)57(40-107)105-71(121)50(24-14-16-30-81)101-68(118)51(25-17-31-89-78(85)86)98-64(114)42(3)94-61(112)39-93-76(126)63(45(6)108)106-74(124)55(35-47-21-11-8-12-22-47)97-62(113)38-91-60(111)37-92-67(117)48(82)34-46-19-9-7-10-20-46/h7-12,19-22,41-45,48-57,63,107-108H,13-18,23-40,80-82H2,1-6H3,(H2,83,109)(H2,84,110)(H,91,111)(H,92,117)(H,93,126)(H,94,112)(H,95,122)(H,96,125)(H,97,113)(H,98,114)(H,99,115)(H,100,119)(H,101,118)(H,102,123)(H,103,116)(H,104,120)(H,105,121)(H,106,124)(H,127,128)(H4,85,86,89)(H4,87,88,90)/t42-,43-,44-,45+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-/m0/s1

InChIKey: PULGYDLMFSFVBL-SMFNREODSA-N


Database reference:
ACToR: ID 170713-75-4

BindingDB: ID 21842

BRENDA: Ligand Nociceptin; Ligand nociceptin/orphanin FQ-NOP receptor system

ChEBI: ID 80266

ChEMBL: ID CHEMBL396460

ChemSpider: ID 17288154

DSigDB: ID d4ttd_9941

EPA CompTox: ID DTXSID60168933

EPA DSSTox: ID DTXCID1091424

EROP-Moscow: ID E02083

FDA SRS: ID 7AYI9N34FF

IUPHAR-DB: ID 1681

J-GLOBAL: ID 200907049682059418

KEGG Compound: ID C16044

Metabolights: ID MTBLC80266

NeuroPep: ID NP04104; NP04141; NP04168; NP04187; NP04197

Nikkaji: ID J764.295D

PepBank: Peptide FGGFTGARKSARKLANQ

PEPlife: ID 2625; 2626

PeptideDB: ID PEP02391; PEP06417; PEP09163

PubChem: CID 16131448

SATPdb: ID satpdb11382