BIOPEP-UWM: Report

ID 9431
Name Renin inhibitor
sequence
QF
Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007)
 
Number of residues
2
Activity code
ren
Activity :
renin inhibitor
Chemical mass 293.3176 Monoisotopic mass 293.1371
IC50 :
0.00 µM


Bibliographic data:
Authors
Udenigwe C.; Li H.; Aluko R.
Title
Quantitative structure-activity relationship modeling of renin-inhibiting dipeptides. Amino Acids, 42, 1379–1386, 2012
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O

InChI=1S/C14H19N3O4/c15-10(6-7-12(16)18)13(19)17-11(14(20)21)8-9-4-2-1-3-5-9/h1-5,10-11H,6-8,15H2,(H2,16,18)(H,17,19)(H,20,21)/t10-,11-/m0/s1

InChIKey: VHLZDSUANXBJHW-QWRGUYRKSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 9431)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database


Database reference:
AHTPDB: ID 2979

BioPepDB: ID biopep01137

BIOPEP-UWM database of bioactive peptides: ID 8870

ChEBI: ID 141430

HMDB: ID HMDB0028804

PubChem: CID 57288566

SATPdb: ID satpdb27517

SureChEMBL: ID SCHEMBL2980533