BIOPEP-UWM: Report

ID 9432
Name Renin inhibitor
sequence
SF
Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007)
 
Number of residues
2
Activity code
ren
Activity :
renin inhibitor
Chemical mass 252.2658 Monoisotopic mass 252.1106
IC50 :
0.00 µM


Bibliographic data:
Authors
Udenigwe C.; Li H.; Aluko R.
Title
Quantitative structure-activity relationship modeling of renin-inhibiting dipeptides. Amino Acids, 42, 1379–1386, 2012
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O

InChI=1S/C12H16N2O4/c13-9(7-15)11(16)14-10(12(17)18)6-8-4-2-1-3-5-8/h1-5,9-10,15H,6-7,13H2,(H,14,16)(H,17,18)/t9-,10-/m0/s1

InChIKey: PPQRSMGDOHLTBE-UWVGGRQHSA-N


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7685); the BRENDA database; the ChEMBL database; the EROP-Moscow database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8891)


Database reference:
AHTPDB: ID 1382, 1696, 1812, 2656, 3267, 3364, 3537, 3584, 4025, 4709, 5172, 5743, 5869, 6671

BioCyc: ID CPD-20388

BioPepDB: ID biopep01237

BIOPEP-UWM database of bioactive peptides: ID 7685; 8891

BRENDA: Ligand Ser-Phe

ChEBI: ID 71029

ChEMBL: ID CHEMBL3321990

ChemSpider: ID 5373177

EROP-Moscow: ID E09344

J-GLOBAL: ID 200907032654367891

Metabolights: ID MTBLC71029

Nikkaji: ID J151.049E

PubChem: CID 7009597

SATPdb: ID satpdb18279

SDBS: ID 8349

SureChEMBL: ID SCHEMBL9622556

ZINC: ID ZINC000002384818