BIOPEP-UWM: Report

ID 9469
Name Renin inhibitor
sequence
RALP

Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007)
 
Number of residues
4
Activity code
ren
Activity :
renin inhibitor
Chemical mass 455.5502 Monoisotopic mass 455.2848
IC50 :
970.00 µM



Bibliographic data:
Authors
He R., Malomo S. A., Alashi A., Girgih A. T., Ju X., Aluko R. E.
Title
Purification and hypotensive activity of rapeseed protein derived renin and angiotensin converting enzyme inhibitory peptides. J. Funct. Foods, 5, 781-789, 2013
Year Source
2013 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C20H37N7O5/c1-11(2)10-14(18(30)27-9-5-7-15(27)19(31)32)26-16(28)12(3)25-17(29)13(21)6-4-8-24-20(22)23/h11-15H,4-10,21H2,1-3H3,(H,25,29)(H,26,28)(H,31,32)(H4,22,23,24)/t12-,13-,14-,15-/m0/s1

InChIKey: DLIFANHAVQERII-AJNGGQMLSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID: 9468)




Database reference:
AHTPDB: ID 2953, 2960, 5548

BioPepDB: ID biopep01176

BIOPEP-UWM: ID 9468

SATPdb: ID satpdb22547