BIOPEP-UWM: Report

ID 9471
Name Renin inhibitor
sequence
TF
Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007)
 
Number of residues
2
Activity code
ren
Activity :
renin inhibitor
Chemical mass 266.2923 Monoisotopic mass 266.1262
IC50 :
3100.00 µM


Bibliographic data:
Authors
He R., Malomo S. A., Alashi A., Girgih A. T., Ju X., Aluko R. E.
Title
Purification and hypotensive activity of rapeseed protein derived renin and angiotensin converting enzyme inhibitory peptides. J. Funct. Foods, 5, 781-789, 2013
Year Source
2013 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O

InChI=1S/C13H18N2O4/c1-8(16)11(14)12(17)15-10(13(18)19)7-9-5-3-2-4-6-9/h2-6,8,10-11,16H,7,14H2,1H3,(H,15,17)(H,18,19)/t8-,10+,11+/m1/s1

InChIKey=IQHUITKNHOKGFC-MIMYLULJSA-N

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 8185); the ChEMBL database; the EROP-Moscow database; the PubChem database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8900)
Inhibitor of Dipeptidyl peptidase III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.003) according to the BIOPEP-UWM database of bioactive peptides (ID:9486


Information concerning Renin is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: A01.007)


Database reference:
AHTPDB: ID 1288, 1360, 1407, 1935, 2735, 2959, 3003, 4030, 4715, 5174, 5547, 6283, 6759

BindingDB: ID 50049727

BioPepDB: ID biopep01280

BIOPEP-UWM database of bioactive peptides: ID 8185; 8900; 9486

BRENDA: Ligand Thr-Phe

ChEBI: ID 74862

ChEMBL: ID CHEMBL3321993

ChemSpider: ID 5374146

EROP-Moscow: ID E04068

J-GLOBAL: ID 200907000712776838

Metabolights: ID MTBLC74862

MoNA: ID MT000062

Nikkaji: ID J307.687C

PubChem: CID 7010580

SATPdb: ID satpdb15566

SureChEMBL: ID SCHEMBL233445

ZINC: ID ZINC000002391070