BIOPEP-UWM: Report

ID 9472
Name Renin inhibitor
sequence
GHS

Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007)
 
Number of residues
3
Activity code
hyp
Activity :
hypotensive
Chemical mass 299.2825 Monoisotopic mass 299.1226
IC50 :
0.00 µM



Bibliographic data:
Authors
He R., Malomo S. A., Alashi A., Girgih A. T., Ju X., Aluko R. E.
Title
Glycinyl-histidinyl-serine (GHS), a novel rapeseed protein-derived peptide has blood pressure-lowering effect in spontaneously hypertensive rats. J. Agric. Food Chem., 61, 8396-8402, 2013
Year Source
2013 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@]([H])(CO)C(=O)O

InChI=1S/C11H17N5O5/c12-2-9(18)15-7(1-6-3-13-5-14-6)10(19)16-8(4-17)11(20)21/h3,5,7-8,17H,1-2,4,12H2,(H,13,14)(H,15,18)(H,16,19)(H,20,21)/t7-,8-/m0/s1

InChIKey: LPCKHUXOGVNZRS-YUMQZZPRSA-N

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9473)




Database reference:
AHTPDB: ID 1053, 2949

BioPepDB: ID biopep00354

BIOPEP-UWM database of bioactive peptides: ID 9473

SATPdb: ID satpdb13065