BIOPEP-UWM: Report

ID 9476
Name DPP-III inhibitor
sequence
YY

Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
2
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 344.3610 Monoisotopic mass 344.1367
EC50 :
0.00 µM



Bibliographic data:
Authors
Lee, C.M.; Snyder, S.H.
Title
Dipeptidylaminopeptidase-III of rat brain selective affinity for enkephalin and angiotensin. J. Biol. Chem., 257, 12043–12050, 1982
Year Source
1982 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)O

InChI=1S/C18H20N2O5/c19-15(9-11-1-5-13(21)6-2-11)17(23)20-16(18(24)25)10-12-3-7-14(22)8-4-12/h1-8,15-16,21-22H,9-10,19H2,(H,20,23)(H,24,25)/t15-,16-/m0/s1

InChIKey: JAQGKXUEKGKTKX-HOTGVXAUSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02.001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9946); the EROP-Moscow database
Inhibitor of Dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8948)
Inhibitor of tyrosyl tRNA synthetase (EC 6.1.1.1) from Staphylococcus aureus according to the ChEMBL database; the PubChem database
Inhibitor of renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the BRENDA database
Inhibitor of tubulin-tyrosine ligase (EC 6.3.2.25) according to the BRENDA database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID: 33)

Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)



Database reference:
ACToR: ID 1050-28-8

AHTPDB: ID 5413

BindingDB: ID BDBM50081840

BioPepDB: ID biopep01645

BIOPEP-UWM database of bioactive peptides: ID 8948; 9946

BIOPEP-UWM database of sensory peptides and amino acids: ID 33

BRENDA: Ligand Tyr-Tyr

ChEBI: ID 60989

ChEMBL: ID CHEMBL95286

ChemIdPlus: ID 1050-28-8

ChemSpider: ID 63759

CTD: ID 1050-28-8

EROP-Moscow: ID E10447

J-GLOBAL: ID 200907087926120458

Metabolights: ID MTBLC60989

Nikkaji: ID J150.479G

PubChem: ID 70590

SATP: ID satpdb13867

SureChEMBL: ID SCHEMBL1574161

ZINC: ID ZINC02004481