BIOPEP-UWM: Report

ID 9477
Name DPP-III inhibitor
sequence
RW
Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
2
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 360.4099 Monoisotopic mass 360.1905
EC50 :
0.00 µM


Bibliographic data:
Authors
Lee, C.M.; Snyder, S.H.
Title
Dipeptidylaminopeptidase-III of rat brain selective affinity for enkephalin and angiotensin. J. Biol. Chem., 257, 12043–12050, 1982
Year Source
1982 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)O

InChI=1S/C17H24N6O3/c18-12(5-3-7-21-17(19)20)15(24)23-14(16(25)26)8-10-9-22-13-6-2-1-4-11(10)13/h1-2,4,6,9,12,14,22H,3,5,7-8,18H2,(H,23,24)(H,25,26)(H4,19,20,21)/t12-,14-/m0/s1

InChIKey=QADCERNTBWTXFV-JSGCOSHPSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8214)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02.001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID:7580), the ChEMBL database; the EROP-Moscow database
Inhibitor of Dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID:8890)
Antiviral peptide according to the AVPdb database
Inhibitor of Xanthine oxidase (EC 1.17.3.2) according to the EROP-Moscow database


Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)


Database reference:
AHTPDB: ID 1221, 1497, 1513, 2058, 2848, 3535, 3783, 4448, 4489, 4658, 6566

AVPdb: ID AVP1529

BindingDB: ID 50407441

BioPepDB: ID biopep01230

BIOPEP-UWM database of bioactive peptides: ID 7580; 8214; 8890

BRENDA: Ligand Arg-Trp

ChEBI: ID 73821

ChEMBL: ID CHEMBL91160

ChemSpider: ID 5373233

EPA CompTox: ID DTXSID00426569

EPA DSSTox: ID DTXSID00426569

EROP-Moscow: ID E10401

J-GLOBAL: ID 200907005445591086

Metabolights: ID MTBLC73821

Nikkaji: ID J36.199B

PubChem: CID 7009653

SATPdb: ID satpdb26916

SureChEMBL: ID SCHEMBL5326395

ZINC: ID ZINC2384977