BIOPEP-UWM: Report

ID 9478
Name DPP-III inhibitor
sequence
LR

Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
2
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 287.3576 Monoisotopic mass 287.1952
EC50 :
0.00 µM



Bibliographic data:
Authors
Lee, C.M.; Snyder, S.H.
Title
Dipeptidylaminopeptidase-III of rat brain selective affinity for enkephalin and angiotensin. J. Biol. Chem., 257, 12043–12050, 1982
Year Source
1982 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C12H25N5O3/c1-7(2)6-8(13)10(18)17-9(11(19)20)4-3-5-16-12(14)15/h7-9H,3-6,13H2,1-2H3,(H,17,18)(H,19,20)(H4,14,15,16)/t8-,9-/m0/s1

InChIKey: SENJXOPIZNYLHU-IUCAKERBSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9213)
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID 2842)

Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 2842, 9213, 10360

BRENDA: Ligand Leu-Arg

ChEBI: ID CHEBI73528

ChemIDplus: ID 026607158

ChemSpider: ID 134773

EROP-Moscow: ID E01608

PubChem: CID 152914

ZINC: ID ZINC02124468