BIOPEP-UWM: Report

ID 9483
Name DPP-III inhibitor
sequence
YK
Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
2
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 309.3599 Monoisotopic mass 309.1683
EC50 :
0.00 µM


Bibliographic data:
Authors
Lee, C.M.; Snyder, S.H.
Title
Dipeptidylaminopeptidase-III of rat brain selective affinity for enkephalin and angiotensin. J. Biol. Chem., 257, 12043–12050, 1982
Year Source
1982 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C15H23N3O4/c16-8-2-1-3-13(15(21)22)18-14(20)12(17)9-10-4-6-11(19)7-5-10/h4-7,12-13,19H,1-3,8-9,16-17H2,(H,18,20)(H,21,22)/t12-,13-/m0/s1

InChIKey=AOLHUMAVONBBEZ-STQMWFEESA-N

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02.001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID: 7697).
Inhibitor of Dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID:8939)


Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)


Database reference:
AHTPDB: ID 1698, 2990, 3028, 3066, 3147, 3169, 3173, 3188, 3271, 3338, 3549, 6683

BioPepDB: ID biopep01573

BIOPEP-UWM database of bioactive peptides: ID 7697; 8939

CHEBI: ID CHEBI:75004

ChEMBL: ID CHEMBL1221518

ChemSpider: ID 5384727

J-GLOBAL: ID 200907074120119951

Metabolights: ID MTBLC75004

MMsINC: ID MMs00484507

Nikkaji: ID J522.537J

PubChem: CID 7021830

SATPdb: ID satpdb27145

SureChEMBL: ID SCHEMBL338636

ZINC: ID ZINC2575131