BIOPEP-UWM: Report

ID 9486
Name DPP-III inhibitor
sequence
TF

Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
2
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 266.2923 Monoisotopic mass 266.1262
EC50 :
0.00 µM



Bibliographic data:
Authors
Lee, C.M.; Snyder, S.H.
Title
Dipeptidylaminopeptidase-III of rat brain selective affinity for enkephalin and angiotensin. J. Biol. Chem., 257, 12043–12050, 1982
Year Source
1982 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O

InChI=1S/C13H18N2O4/c1-8(16)11(14)12(17)15-10(13(18)19)7-9-5-3-2-4-6-9/h2-6,8,10-11,16H,7,14H2,1H3,(H,15,17)(H,18,19)/t8-,10+,11+/m1/s1

InChIKey=IQHUITKNHOKGFC-MIMYLULJSA-N

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 8185); the ChEMBL database; the EROP-Moscow database; the PubChem database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8900)
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID 9471)

Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)




Database reference:
AHTPDB: ID 1288, 1360, 1407, 1935, 2735, 2959, 3003, 4030, 4715, 5174, 5547, 6283, 6759

BindingDB: ID 50049727

BioPepDB: ID biopep01280

BIOPEP-UWM database of bioactive peptides: ID 8185; 8900; 9471

BRENDA: Ligand Thr-Phe

ChEBI: ID 74862

ChEMBL: ID CHEMBL3321993

ChemSpider: ID 5374146

EROP-Moscow: ID E04068

J-GLOBAL: ID 200907000712776838

Metabolights: ID MTBLC74862

MoNA: ID MT000062

Nikkaji: ID J307.687C

PubChem: CID 7010580

SATPdb: ID satpdb15566

SureChEMBL: ID SCHEMBL233445

ZINC: ID ZINC000002391070