BIOPEP-UWM: Report

ID 9490
Name DPP-III inhibitor
sequence
RF
Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
2
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 321.3739 Monoisotopic mass 321.1796
IC50 :
0.00 µM


Bibliographic data:
Authors
Dhanda S.; Singh H.; Singh J.
Title
Hydrolysis of various bioactive peptides by goat brain dipeptidylpeptidase-III. Cell Biochem. Funct. 23, 3, 339–345.
Year Source
2008 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C15H23N5O3/c16-11(7-4-8-19-15(17)18)13(21)20-12(14(22)23)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,16H2,(H,20,21)(H,22,23)(H4,17,18,19)/t11-,12-/m0/s1

InChIKey=PQBHGSGQZSOLIR-RYUDHWBXSA-N


Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)

Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides (ID 3489), the BRENDA database, the ChEMBL database, the EROP-Moscow database and the PubChem database
Inhibitor of UBR protein in rabbit reticulocyte lysates according to the PubChem database
Inhibitor of dipeptidyl peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9490), the BRENDA database
Inhibitor of leucyltransferase (EC 2.3.2.6) according to the BRENDA database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 13)

Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7) according to the BIOPEP-UWM Virtual database (ID 62)


Database reference:
ACToR: ID 2047-13-4

AHTPDB: ID 1184; 1251; 1370; 1505; 1666; 1921; 3202; 3793; 4019; 4110; 4242; 4439; 4499; 4688; 4961; 4962; 5425; 5450; 5567; 5620; 5860; 6155; 6408

BindingDB: ID 50407425

BIOPEP-UWM database of bioactive peptides: ID 3489

BIOPEP-UWM database of sensory peptides and amino acids: ID 13

BIOPEP-UWM Virtual database: ID 62

BRENDA: Ligand Arg-Phe

ChEBI: ID 73818

ChEMBL: ID CHEMBL92255

ChemIDPlus: ID 2047-13-4

ChemSpider: ID 133060

EROP-Moscow: ID E00282

J-Global: ID 200907001510653641

Metabolights: ID MTBLC73818

Nikkaji: ID J80.373A

PubChem: CID 150964

SATPdb: ID satpdb13865

SureChEMBL: ID SCHEMBL1737558

ZINC: ID ZINC02384822