BIOPEP-UWM: Report

ID 9527
Name Antioxidant peptide from ApGR (GR enzyme from Arthrospira platensis)
sequence
GGTCVIRGCVPKKLM
Function:
The oxidant scavenging ability of the peptide leads positive implications in reducing free radicals in leucocytes during oxidative stress
 
Number of residues
15
Activity code
ao
Activity :
antioxidative
Chemical mass 1561.9763 Monoisotopic mass 1560.8276
EC50 :
0.00 µM


Bibliographic data:
Authors
Sannasimuthu A, Kumaresan V, Anilkumar S, Pasupuleti M, Ganesh MR, Mala K, Paray BA, Al-Sadoon MK, Albeshr MF, Arockiaraj J
Title
Design and characterization of a novel Arthrospira platensis glutathione oxido-reductase-derived antioxidant peptide GM15 and its potent anti-cancer activity via caspase-9 mediated apoptosis in oral cancer cells. Free Radical Biol Med 135:198-209, 20
Year Source
2019 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)NCC(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C66H120N20O17S3/c1-11-37(8)52(85-61(98)50(35(4)5)83-59(96)45(33-105)81-63(100)53(38(9)87)82-49(90)30-73-47(88)29-69)62(99)78-39(20-16-25-72-66(70)71)54(91)74-31-48(89)75-44(32-104)58(95)84-51(36(6)7)64(101)86-26-17-21-46(86)60(97)77-41(19-13-15-24-68)55(92)76-40(18-12-14-23-67)56(93)80-43(28-34(2)3)57(94)79-42(65(102)103)22-27-106-10/h34-46,50-53,87,104-105H,11-33,67-69H2,1-10H3,(H,73,88)(H,74,91)(H,75,89)(H,76,92)(H,77,97)(H,78,99)(H,79,94)(H,80,93)(H,81,100)(H,82,90)(H,83,96)(H,84,95)(H,85,98)(H,102,103)(H4,70,71,72)/t37-,38+,39-,40-,41-,42-,43-,44-,45-,46-,50-,51-,52-,53-/m0/s1

InChIKey=WQCJCQVRLBZENI-ZAQIAUEHSA-N

Anticancer peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9528).


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9528