BIOPEP-UWM: Report

ID 9537
Name Anti-inflammatory peptide
sequence
IPP
Function:
Inhibitor of inflammation
 
Number of residues
3
Activity code
ai
Activity :
anti inflammatory
Chemical mass 325.4022 Monoisotopic mass 325.1995
EC50 :
0.00 µM


Bibliographic data:
Authors
Chakrabarti S., Wu J.
Title
Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) promote adipocyte differentiation and inhibit inflammation in 3T3-F442A cells. PLoS ONE, 10, Article No e0117492, 2015
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(CC)[C@]([H])(N)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C16H27N3O4/c1-3-10(2)13(17)15(21)18-8-4-6-11(18)14(20)19-9-5-7-12(19)16(22)23/h10-13H,3-9,17H2,1-2H3,(H,22,23)/t10-,11-,12-,13-/m0/s1

InChIKey=FQYQMFCIJNWDQZ-CYDGBPFRSA-N


Review concerning the peptide:
Li S., Bu T., Zheng J., Liu L., He G., Wu J., 2019, Preparation, bioavailability, and mechanism of emerging activities of Ile-Pro-Pro and Val-Pro-Pro. Compr. Rev. Food Sci. Food Saf., 18, 1097-1110


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 3522); the ChEMBL database; the EROP-Moscow database; the MBPDB database
Inhibitor of the Angiotensin 2-converting enzyme (EC 3.4.17.23) (MEROPS ID: M02.006) according to the BRENDA database


Database reference:
AHTPDB: ID 1147, 1276, 1545, 1625, 1672, 1710, 2008, 2243, 2741, 2970, 3402, 3629, 3732, 3775, 3954, 4081, 4177, 4750, 4965, 4966, 5126, 5219, 5514, 5573, 6046, 6093, 6440

BindingDB: ID 50169149

BioPepDB: ID biopep00562

BIOPEP-UWM database of bioactive peptides: ID 3522

BRENDA: Ligand Ile-Pro-Pro

ChEMBL: ID CHEMBL190994

ChemIDplus: ID 26001-32-1

ChemSpider: ID 8124823

CTD: ID 26001-32-1

DSLD: compound Isoleucyl-prolyl-proline

Drug Information Portal: ID 26001-32-1

eChemPortal: ID 26001-32-1

EROP-Moscow: ID E07047

J-GLOBAL: ID 200907029257440891

MBPDB: Peptide IPP

Nikkaji: ID J667.339B

PubChem: CID 9949212

SATPdb: ID satpdb14611

SureChEMBL: ID SCHEMBL1646849

ZINC: ID ZINC000013646353