BIOPEP-UWM: Report
| ID | 9538 |
| Name | Anti-inflammatory peptide |
| sequence |
| Function: | |||
| Inhibitor of inflammation | |||
| Number of residues | 3 |
Activity code | ai |
| Activity : | anti inflammatory |
|||
| Chemical mass | 311.3757 | Monoisotopic mass | 311.1839 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Chakrabarti S., Wu J. | |
| Title | |
| Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) promote adipocyte differentiation and inhibit inflammation in 3T3-F442A cells. PLoS ONE, 10, Article No e0117492, 2015 | |
| Year | Source |
| 2015 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C15H25N3O4/c1-9(2)12(16)14(20)17-7-3-5-10(17)13(19)18-8-4-6-11(18)15(21)22/h9-12H,3-8,16H2,1-2H3,(H,21,22)/t10-,11-,12-/m0/s1 InChIKey=DOFAQXCYFQKSHT-SRVKXCTJSA-N Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 Review concerning the peptide: Li S., Bu T., Zheng J., Liu L., He G., Wu J., 2019, Preparation, bioavailability, and mechanism of emerging activities of Ile-Pro-Pro and Val-Pro-Pro. Compr. Rev. Food Sci. Food Saf., 18, 1097-1110 Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 3524); the ChEMBL database; the EROP-Moscow database; the MBPDB database Inhibitor of the Angiotensin 2-converting enzyme (EC 3.4.17.23) (MEROPS ID: M02.006) according to the BRENDA database |
| Database reference: |
| AHTPDB: ID 1200, 1275, 1583, 1671, 1711, 2009, 2244, 2740, 2971, 3205, 3403, 3589, 3628, 3735, 3774, 4043, 4122, 4178, 4799, 4963, 4964, 5125, 5262, 5515, 5572, 5629, 6092, 6442 BindingDB: ID 50169128 BioPepDB: ID biopep01435 BIOPEP-UWM database of bioactive peptides: ID 3524 BRENDA: Ligand Val-Pro-Pro ChEBI: ID 73696 ChEMBL: ID CHEMBL190414 ChemIdPlus: ID 58872-39-2 ChemSpider: ID 7993950 Drug Information Portal: ID 58872-39-2 EROP-Moscow: ID E07046 FDA SRS: ID 2U1R84870F J-GLOBAL: ID 200907032217042614 MBPDB: Peptide VPP Metabolights: ID MTBLC73696 Nikkaji: ID J667.338D PubChem: CID 9818200 SATPdb: ID satpdb19459 SureChEMBL: ID SCHEMBL1644894 ZINC: ID ZINC000013646338 |