BIOPEP-UWM: Report

ID 9543
Name ACE inhibitor
sequence
RYL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 450.5305 Monoisotopic mass 450.2583
IC50 :
3.31 µM


Bibliographic data:
Authors
Liu L., Wei Y. N., Chang Q., Sun H. J., Chai K. G., Huang Z. Q., Zhao, Z. X., Zhao Z. X.
Title
Ultrafast screening of a novel, moderately hydrophilic Angiotensin-converting-enzyme-inhibitory peptide, RYL, from silkworm pupa using an fe-doped-silkworm-excrement-derived biocarbon: waste conversion by waste. J. Agric. Food Chem., 65, 11202-11211,
Year Source
2017 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C21H34N6O5/c1-12(2)10-17(20(31)32)27-19(30)16(11-13-5-7-14(28)8-6-13)26-18(29)15(22)4-3-9-25-21(23)24/h5-8,12,15-17,28H,3-4,9-11,22H2,1-2H3,(H,26,29)(H,27,30)(H,31,32)(H4,23,24,25)/t15-,16-,17-/m0/s1

InChIKey: CGWVCWFQGXOUSJ-ULQDDVLXSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001

Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10052); the MBPDB database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10052

ChEBI: ID 159415

EROP-Moscow: ID E23959

MBPDB: Peptide RYL

PubChem: CID 145453978