BIOPEP-UWM: Report

ID 9545
Name DPPIV inhibitor
sequence
GIPLPLI
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
7
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 721.9250 Monoisotopic mass 721.4723
IC50 :
3.83 µM


Bibliographic data:
Authors
Ashok A., Aparna B. H. S.
Title
Discovery, synthesis, and in vitro evaluation of a novel bioactive peptide for ACE and DPP-IV inhibitory activity. Eur. J. Med. Chem., 180, 99-110, 2019
Year Source
2019 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)O

InChI=1S/C36H63N7O8/c1-9-22(7)29(40-28(44)19-37)35(49)43-16-12-14-27(43)33(47)39-25(18-21(5)6)34(48)42-15-11-13-26(42)32(46)38-24(17-20(3)4)31(45)41-30(36(50)51)23(8)10-2/h20-27,29-30H,9-19,37H2,1-8H3,(H,38,46)(H,39,47)(H,40,44)(H,41,45)(H,50,51)/t22-,23-,24-,25-,26-,27-,29-,30-/m0/s1


InChIKey=MSHLQYRYTWUMNE-PXCFLYLPSA-N


Database reference: