BIOPEP-UWM: Report

ID 9556
Name DPPIV inhibitor
sequence
VPYPQ
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
5
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 602.6775 Monoisotopic mass 602.3054
IC50 :
41.45 µM


Bibliographic data:
Authors
Zheng L., Xu Q., Lin L., Zeng X., Sun B., Zhao M. M.
Title
In vitro metabolic stability of a casein-derived dipeptidyl peptidase-IV (DPP-IV) inhibitory peptide VPYPQ and its controlled release from casein by enzymatic hydrolysis. J. Agric. Food Chem., 67, 10604-10613, 2019
Year Source
2019 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C29H42N6O8/c1-16(2)24(31)28(41)35-14-4-6-22(35)26(39)33-20(15-17-7-9-18(36)10-8-17)27(40)34-13-3-5-21(34)25(38)32-19(29(42)43)11-12-23(30)37/h7-10,16,19-22,24,36H,3-6,11-15,31H2,1-2H3,(H2,30,37)(H,32,38)(H,33,39)(H,42,43)/t19-,20-,21-,22-,24-/m0/s1

InChIKey= PNRCORVXKCNAOX-YGQNSOCVSA-N

Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8278); the MBPDB database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8278

ChemSpider: ID 9759987

EPA DSSTox: ID DTXCID80419772

EROP-Moscow: ID E23724

FeptideDB: ID 8278

MBPDB: Peptide VPYPQ

PubChem: CID 11585222