BIOPEP-UWM: Report
| ID | 9557 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 6 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 603.6916 | Monoisotopic mass | 603.2790 | |
| IC50 : | 23.94 µM |
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| Bibliographic data: | |
| Authors | |
| Deng Z., Liu Y., Wang J., Wu S., Geng L., Sui Z., Zhang Q. | |
| Title | |
| Antihypertensive effects of two novel angiotensin I-converting enzyme (ACE) inhibitory peptides from Gracilariopsis lemaneiformis (Rhodophyta) in spontaneously hypertensive rats (SHRs). Mar. Drugs, 16, Article No 299, 2018 | |
| Year | Source |
| 2018 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O InChI=1S/C23H41N9O8S/c1-11(29-16(34)9-28-20(37)17(24)12(2)33)21(38)32-8-4-6-15(32)19(36)31-14(10-41)18(35)30-13(22(39)40)5-3-7-27-23(25)26/h11-15,17,33,41H,3-10,24H2,1-2H3,(H,28,37)(H,29,34)(H,30,35)(H,31,36)(H,39,40)(H4,25,26,27)/t11-,12+,13-,14-,15-,17-/m0/s1 InChIKey: VEVGFNGDPJDSTM-ODIPTECFSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 The peptide causes decrease of blood pressure in spontaneously hypertensive rats. |
| Database reference: |