BIOPEP-UWM: Report

ID 9578
Name DPP-III inhibitor
sequence
YAGFL
Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
5
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 569.6477 Monoisotopic mass 569.2840
EC50 :
0.00 µM


Bibliographic data:
Authors
Barsun M., Jajcanin N., Vukelic B., Spoljaric J., Abramic M.
Title
Human dipeptidyl peptidase III acts as a post-prolinecleaving enzyme on endomorphins. Biological Chemistry, 388, 343–348, 2007
Year Source
2007 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22-,23-,24-/m0/s1

InChIKey= ZHUJMSMQIPIPTF-IMNFJDCFSA-N

Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)


Inhibitor of DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) according to the ChEMBL database


Database reference:
BRENDA: Ligand Tyr-Ala-Gly-Phe-Leu

ChEMBL: ID CHEMBL266834

ChemSpider: ID 23113321

EPA CompTox: ID DTXSID60515342

EPA DSSTox: ID DTXCID20466149

J-GLOBAL: ID 200907098601212390

Nikkaji: ID J1.261.661I

PepBank: Peptide YAGFL

PubChem: CID 26757061

SureChEMBL: ID SCHEMBL11683986

ZINC: ID ZINC000017654732