BIOPEP-UWM: Report

ID 9632
Name DPP-III inhibitor
sequence
LVVYPWT
Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
7
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 877.0347 Monoisotopic mass 876.4730
EC50 :
0.00 µM


Bibliographic data:
Authors
Chiba, T.; Li, Y.; Yamane, T.; Ogikubo, O.; Fukuoka, M.; Arai, R.; Takahashi, S.; Ohtsuka, T.; Ohkubo, I.; Matsui, N.
Title
Inhibition of recombinant dipeptidyl peptidase III by synthetic hemorphin-like peptides. Peptides, 24, 773–778, 2003
Year Source
2003 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC3=C[N]([H])C4=CC=CC=C34)C(=O)N[C@@H]([C@H](O)C)C(=O)O

InChI=1S/C45H64N8O10/c1-23(2)19-31(46)39(56)50-37(25(5)6)43(60)51-36(24(3)4)42(59)49-34(20-27-14-16-29(55)17-15-27)44(61)53-18-10-13-35(53)41(58)48-33(40(57)52-38(26(7)54)45(62)63)21-28-22-47-32-12-9-8-11-30(28)32/h8-9,11-12,14-17,22-26,31,33-38,47,54-55H,10,13,18-21,46H2,1-7H3,(H,48,58)(H,49,59)(H,50,56)(H,51,60)(H,52,57)(H,62,63)/t26-,31+,33+,34+,35+,36+,37+,38+/m1/s1

InChIKey=BXIFNVGZIMFBQB-DYDSHOKNSA-N


Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)

Neuropeptide according to the BIOPEP-UWM database of bioactive peptides (ID 9255), the ChEMBL database, the PepBank database
Cytotoxic peptide according to the EROP-Moscow database


Database reference:
ACToR: ID 137201-62-8

BindingDB: ID 50219120

BIOPEP-UWM database of bioactive peptides: ID 9255

ChEMBL: ID CHEMBL395493

ChemIDplus: ID 137201628

ChemSpider: ID 2339355

DSigDB: ID d4ttd_11043, d4ctd_2995

EPA CompTox Dashboard: ID DTXSID70160105

EPA DSSTox: ID DTXCID3082596

EROP-Moscow: ID E01885

Human Metabolome Database: ID HMDB59790

J-GLOBAL: ID 200907027456681757

Nikkaji: ID J555.836K

PepBank: Peptide LVVYPWT

PubChem: CID 3081832

ZINC: ID ZINC000150339235