BIOPEP-UWM: Report

ID 9635
Name DPP-III inhibitor - VV-hemorphin-5
sequence
VVYPWTQ
Function:
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001)
 
Number of residues
7
Activity code
dpp3
Activity :
dipeptidyl peptidase III inhibitor
Chemical mass 892.0064 Monoisotopic mass 891.4476
EC50 :
0.00 µM


Bibliographic data:
Authors
Barsun M., Jajcanin N., Vukelic B., Spoljaric J., Abramic M.
Title
Human dipeptidyl peptidase III acts as a post-prolinecleaving enzyme on endomorphins. Biological Chemistry, 388, 343–348, 2007
Year Source
2007 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC3=C[N]([H])C4=CC=CC=C34)C(=O)N[C@@H]([C@H](O)C)C(=O)N[C@@H](CCC(=O)N)C(=O)O

InChI=1S/C44H61N9O11/c1-22(2)35(46)40(59)51-36(23(3)4)41(60)50-32(19-25-12-14-27(55)15-13-25)43(62)53-18-8-11-33(53)39(58)49-31(20-26-21-47-29-10-7-6-9-28(26)29)38(57)52-37(24(5)54)42(61)48-30(44(63)64)16-17-34(45)56/h6-7,9-10,12-15,21-24,30-33,35-37,47,54-55H,8,11,16-20,46H2,1-5H3,(H2,45,56)(H,48,61)(H,49,58)(H,50,60)(H,51,59)(H,52,57)(H,63,64)/t24-,30+,31+,32+,33+,35+,36+,37+/m1/s1

InChIKey= VAEOIFAHJWMTKD-NMUVPRMFSA-N


Information concerning Dipeptidyl peptidase-III (DPP-III) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M49.001)

Opioid peptide according to the BIOPEP-UWM database of bioactive peptides (ID 2571)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9277)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 2571; 9277

ChemSpider: ID 8661301

EROP-Moscow: ID E01091

PepBank: Peptide VVYPWTQ

PubChem: CID 10485896