BIOPEP-UWM: Report

ID 9655
Name Antihypertensive peptide derived from spinach Rubisco
sequence
MRWRD

Function:
Antihypertensive effect after oral administration to spontaneously hypertensive rats
 
Number of residues
5
Activity code
hyp
Activity :
hypotensive
Chemical mass 762.8791 Monoisotopic mass 762.3585
EC50 :
0.00 µM



Bibliographic data:
Authors
Yang Y., Marczak E.D., Yokoo M., Usui H., Yoshikawa M.
Title
Isolation and antihypertensive effect of angiotensin I-converting enzyme (ACE) inhibitory peptides from spinach Rubisco. J. Agric. Food. Chem., 51(17): 4897-4902, 2003
Year Source
2003 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)O

InChI=1S/C32H50N12O8S/c1-53-13-10-19(33)26(47)41-21(8-4-11-38-31(34)35)27(48)43-23(14-17-16-40-20-7-3-2-6-18(17)20)29(50)42-22(9-5-12-39-32(36)37)28(49)44-24(30(51)52)15-25(45)46/h2-3,6-7,16,19,21-24,40H,4-5,8-15,33H2,1H3,(H,41,47)(H,42,50)(H,43,48)(H,44,49)(H,45,46)(H,51,52)(H4,34,35,38)(H4,36,37,39)/t19-,21-,22-,23-,24-/m0/s1

InChIKey: SMZWMXSYYZOAMD-DUSBTPNUSA-N


Inhibitor of Angiotensin-converting enzyme (ACE) (EC 3.4.15.1; MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9664) the EROP-Moscow database



Database reference:
AHTPDB: ID 1922, 2315, 2573, 5331, 6228

BioPepDB: ID biopep00982

BIOPEP-UWM database of bioactive peptides: ID 9664

ChemSpider: ID 818594

EROP-Moscow: ID E09161

J-GLOBAL: ID 200907009703006687

Nikkaji: ID J1.754.753D

PubChem: CID 10010362

SATPdb: ID satpdb13657