BIOPEP-UWM: Report

ID 9656
Name Antihypertensive peptide derived from spinach Rubisco
sequence
IAYKPAG
Function:
Antihypertensive effect after oral administration to spontaneously hypertensive rats
 
Number of residues
7
Activity code
hyp
Activity :
hypotensive
Chemical mass 718.8386 Monoisotopic mass 718.4001
EC50 :
0.00 µM


Bibliographic data:
Authors
Yang Y., Marczak E.D., Yokoo M., Usui H., Yoshikawa M.
Title
Isolation and antihypertensive effect of angiotensin I-converting enzyme (ACE) inhibitory peptides from spinach Rubisco. J. Agric. Food. Chem. 51(17): 4897-4902, 2003
Year Source
2003 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)O

InChI=1S/C34H54N8O9/c1-5-19(2)28(36)33(50)39-21(4)30(47)41-25(17-22-11-13-23(43)14-12-22)31(48)40-24(9-6-7-15-35)34(51)42-16-8-10-26(42)32(49)38-20(3)29(46)37-18-27(44)45/h11-14,19-21,24-26,28,43H,5-10,15-18,35-36H2,1-4H3,(H,37,46)(H,38,49)(H,39,50)(H,40,48)(H,41,47)(H,44,45)/t19-,20-,21-,24-,25-,26-,28-/m0/s1

InChIKey=GPOHMCMFILTZSA-NTHYOZQESA-N

Inhibitor of Angiotensin-converting enzyme (ACE) (EC 3.4.15.1; MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9665); the EROP-Moscow database


Database reference:
AHTPDB: ID 2329, 2576, 6227

BioPepDB: ID biopep00493

BIOPEP-UWM database of bioactive peptides: ID 9665

EROP-Moscow: ID E09160

PubChem: CID 25003677

SATPdb: ID satpdb15752