BIOPEP-UWM: Report

ID 9676
Name Hypocholesterolemic peptide
sequence
GQEQSHQDEGVIVR

Function:
Hypocholesterolemic
 
Number of residues
14
Activity code
hypc
Activity :
hypocholesterolemic
Chemical mass 1581.6388 Monoisotopic mass 1580.7519
EC50 :
0.00 µM



Bibliographic data:
Authors
Lammi C., Bollati C., Lecca D., Abbracchio M. P., Arnoldi A.
Title
Lupin peptide T9 (GQEQSHQDEGVIVR) modulates the mutant PCSK9D374Y pathway: in vitro characterization of its dual hypocholesterolemic behavior. Nutrients, 11, 1665, 2019
Year Source
2019 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C[N]([H])C=N1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

InChI=1S/C64H104N22O25/c1-7-30(6)51(62(109)85-50(29(4)5)60(107)80-37(63(110)111)9-8-20-72-64(69)70)86-61(108)49(28(2)3)84-45(92)25-73-52(99)32(13-18-46(93)94)76-58(105)39(22-48(97)98)82-55(102)34(11-16-42(67)89)79-57(104)38(21-31-24-71-27-74-31)81-59(106)40(26-87)83-56(103)35(12-17-43(68)90)77-54(101)36(14-19-47(95)96)78-53(100)33(10-15-41(66)88)75-44(91)23-65/h24,27-30,32-40,49-51,87H,7-23,25-26,65H2,1-6H3,(H2,66,88)(H2,67,89)(H2,68,90)(H,71,74)(H,73,99)(H,75,91)(H,76,105)(H,77,101)(H,78,100)(H,79,104)(H,80,107)(H,81,106)(H,82,102)(H,83,103)(H,84,92)(H,85,109)(H,86,108)(H,93,94)(H,95,96)(H,97,98)(H,110,111)(H4,69,70,72)/t30-,32-,33-,34-,35-,36-,37-,38-,39-,40-,49-,50-,51-/m0/s1

InChIKey: NPIMHQRCKGHZLZ-TUVARWSOSA-N



Database reference: