BIOPEP-UWM: Report

ID 9697
Name Anticancer peptide
sequence
AISCYNGATSYNQKFK
Function:
Active against murine melanoma cells
 
Number of residues
16
Activity code
ac
Activity :
anticancer
Chemical mass 1794.9772 Monoisotopic mass 1793.8379
EC50 :
71.40 µM


Bibliographic data:
Authors
Polonelli L., Pontón J., Elguezabal N., Moragues M.D., Casoli C., Pilotti E., Ronzi P., Dobroff A.S., Rodrigues E.G., Juliano M.A., et al.
Title
Antibody Complementarity-Determining Regions (CDRs) Can Display Differential Antimicrobial, Antiviral and Antitumor Activities. PLoS One. 3(6): e2371. 2008
Year Source
2008 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(N)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC1=CC=C(O)C=C1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CC=C(O)C=C1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC1=CC=CC=C1)C(=O)N[C@@]([H])(CCCCN)C(O)=O)[C@@]([H])(C)O)[C@@]([H])(C)CC

InChI=1S/C79H119N21O25S/c1-6-39(2)63(99-65(110)40(3)82)77(122)96-57(37-102)75(120)98-58(38-126)76(121)93-53(32-45-20-24-47(105)25-21-45)71(116)94-54(33-60(84)107)67(112)86-35-62(109)87-41(4)66(111)100-64(42(5)103)78(123)97-56(36-101)74(119)92-52(31-44-18-22-46(104)23-19-44)72(117)95-55(34-61(85)108)73(118)89-49(26-27-59(83)106)69(114)88-48(16-10-12-28-80)68(113)91-51(30-43-14-8-7-9-15-43)70(115)90-50(79(124)125)17-11-13-29-81/h7-9,14-15,18-25,39-42,48-58,63-64,101-105,126H,6,10-13,16-17,26-38,80-82H2,1-5H3,(H2,83,106)(H2,84,107)(H2,85,108)(H,86,112)(H,87,109)(H,88,114)(H,89,118)(H,90,115)(H,91,113)(H,92,119)(H,93,121)(H,94,116)(H,95,117)(H,96,122)(H,97,123)(H,98,120)(H,99,110)(H,100,111)(H,124,125)/t39-,40-,41-,42+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,63-,64-/m0/s1

InChIKey: MESDAZIOCWFWRZ-QPPGEXDWSA-N


Antifungal peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9662)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9662